Basophilic leukemia in recurrent chronic myelogenous leukemia blast phase
نویسندگان
چکیده
منابع مشابه
Basophilic blast phase of chronic myelogenous leukemia.
A 29-year-old man with an 8-year history of chronic myeloid leukemia (CML) was referred to our institution for marked leukocytosis and 3% blasts (white blood cells [WBC], 338.7 3 10/L; neutrophils, 159.2 3 10/L; myelocytes, 88.1 3 10/L; basophils, 47.43 10/L) (panel A). Cytogenetic studies showed t(9;22)(q34;q11.2), and the diagnosis of CML, chronic phase, was confirmed. The treatment history i...
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Background: Chronic myelogenous leukemia (CML) is a myeloproliferative disorder due to BCR-ABL1 translocation. Patients showing transformation into blast crisis (BC) have poorer treatment response and prognosis. Methods: A retrospective study was conducted in the department of Pathology, Maulana Azad Medical College, New Delhi, India, over a time period of 5 years (2014-2019) to evaluate the ...
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Blood or bone marrow specimens from 22 patients with chronic myelogenous leukemia in blast crisis were studied for the surface expression of glycophorin-A, a marker for early erythroid differentiation. The leukemic blasts were stained with rabbit anti-glycophorin-A antiserum. The glycophorin-A molecules detected by the rabbit antiserum were identified by polyacrylamide slab gel electrophoresis ...
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T-lymphoblastic leukemia/lymphoma (T-ALL) presenting as blast phase of chronic myelogenous leukemia (CML-BP) is rare. In patients without history of CML, it is difficult to differentiate between CML-BP or de novo T-ALL. Here we reported 2 unusual cases of T-ALL presenting as CML-BP. Case 1 was a 24-year-old female with leukocytosis. Besides T-lymphoblasts (32%), her marrow exhibited some morpho...
متن کاملPromyelocytic blast crisis of chronic myelogenous leukemia.
A 26-year-old male was evaluated for chest pain and was found to have a white cell count of 63 000 per cubic millimeter, hemoglobin 10.5 g/dL, platelets 102 000 per L, with 18% blasts and promyelocytes (panel A). Bone marrow was hypercellular, with promyelocytes and myeloblasts (panel B), some with deeply clefted nuclei. This was morphologically consistent with acute promyelocytic leukemia hype...
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ژورنال
عنوان ژورنال: American Journal of Hematology
سال: 2007
ISSN: 0361-8609,1096-8652
DOI: 10.1002/ajh.20920